Cannabidiol(CBD) is a natural compound that has been increasingly researched due to its significant medicinal effects. CBD is one of at least 60 active cannabinoids identified and is considered to have a wider scope of medical applications and benefits than the THC (tetrahydrocannabinol) element of the  plant.

In recent years an orally-administered extract containing CBD has received orphan drug status in the US. Below is a list of the most common pros and cons for CBD.

Key Benefits:

  • Cannabidiol can counter the psychoactivity of THC and reduce the side effects that would generally make people feel “stoned” and or “high”.
  • The reduced psychoactivity of CBD-rich strains makes it such an appealing treatment option for patients seeking cancer, epilepsy, pain relief, anti-inflammatory, anti-anxiety, anti-psychotic, and/or anti-spasm effects without disconcerting lethargy or dysphoria.
  • CBD can also be used as a treatment for a wide range of conditions, including rheumatoid arthritis, diabetes, alcoholism, MS, chronic pain, schizophrenia, PTSD, antibiotic-resistant infections, and other neurological disorders.
  • A preclinical study by Dr. Sean McAllister and his colleagues at the California Pacific Medical Center in San Francisco reports on how CBD stops the growth of breast cancer by down-regulating a gene called ID-1, which is implicated in several types of aggressive cancer. Silencing the ID-1 gene is thus is an excellent strategy for a cancer treatment.
  • Cannabidiol offers hope of a non-toxic therapy that could treat aggressive forms of cancer without any of the painful side effects of chemotherapy.
  • Clinical studies conducted outside the United States have shown that CBD is an effective painkiller – particularly for peripheral neuropathy associated with cancer, multiple sclerosis, diabetes, arthritis, and other neurodegenerative conditions.
  • CBD has demonstrated neuroprotective and neurogenic effects, and its anti-cancer properties are currently being investigated at several academic research centers in the United States and elsewhere.
  • CBD-rich strains and products are now accessible to medical users after decades in which only high-THC strains were available.
  • According to an untested hypothesis CBD applied through the skin may reduce the sebum production at the root of acne.
  • Recently the synergistic contributions of cannabidiol to cannabis pharmacology have been scientifically demonstrated. Other phytocannabinoids, including tetrahydrocannabivarin, cannabigerol and cannabichromene, exert additional effects of therapeutic interest.
  • CBD interacts synergistically with THC and enhances THC’s painkilling impact, while muting THC’s psychoactivity.
  • CBD can also neutralize unfavorable effects that THC may cause, such as anxiety and rapid heartbeat.
  • There has never been a documented human fatality solely from overdosing on CBD or THC in its natural form.